Digital transformation in the Biological Sciences: A comprehensive perspective from the discipline of biosciences within the Future Professors Programme
Abstract
The concept of digital transformation (DT) has revolutionized different facets of society including institutions of learning, where it has continued to influence teaching, learning and research. Over time and with the continued technological advancements in biological science disciplines, it has become clear that the increased convergence between these disciplines and digital systems application will become more apparent. For example, the advent and application of next-generation sequencing (NGS), machine learning (ML), artificial intelligence (AI) and other automated biological processes have afforded unique huge data sets with high societal impact. As such, digitalization of the bioeconomy remains necessary. The digitalization of the biosciences has birthed emerging concepts like “digital biology”, “engineered biology” and “bio-revolution” and involve computer-centered biosciences. These are built around the integration of scientific data, modeling at several levels, as well as networked science. Nonetheless, it is still plagued by information derivation policies and technicality issues. Although, digital biology has seen a major boost in recent years with the emergence of new and updated digital biology databases and platforms for advanced computational modelling, and connection and visualization of bio-data at a molecular level, more efforts are needed from governmental stakeholders (policy makers), industry and academia to enhance the impact of computational automation and digital transformation in bioscience activities. Hence, a steady upscale in digitalization of the biosciences would ensure bioprocess development, increase teaching, research efficiency and productivity, birth more innovative future applications for various industries, and thereby impact several aspects of life. This article presents how selected biological science disciplines have been digitally transformed through data analytics and how the concept could be further explored in advancing teaching, learning and research.
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Aditya, Bayu Rima, Ridi Ferdiana, and Sri S. Kusumawardani. 2022. “Identifying and prioritizing barriers to digital transformation in higher education: A case study in Indonesia.” International Journal of Innovation Science 14: 445‒460.
Agrawal, Gaurav, Hemant Ahlawat, and Martin Dewhurst. 2021. “Biopharma 2020: A landmark year and a reset for the future.” https://www.mckinsey.com/industries/life-sciences/our-insights/biopharma-2020-a-landmark-year-and-a-reset-for-the-future. (Accessed 20 November 2023).
Akoonjee, Ayesha, Athika Rampadarath, Christiana Eleojo Aruwa, Taibat Arinola Ajiboye, Abdulwakeel Ayokun-nun Ajao, and Saheed Sabiu. 2022. “Network pharmacology-and molecular dynamics simulation-based bioprospection of Aspalathus linearis for type-2 diabetes care.” Metabolites 12(11): 1013.
Alenezi, Mamdouh. 2021. “Deep dive into digital transformation in higher education.” Education Sciences 11: 770.
Alzahrani, Bandar, Haitham Bahaitham, Murad Andejany, and Ahmad Elshennawy. 2021. “How ready is higher education for quality 4.0 transformation according to the Lns research framework?” Sustainability 13: 5169.
Aribisala, Jamiu Olaseni, Christiana Eleojo Aruwa, Taofik Olatunde Uthman, Ismaila Olanrewaju Nurain, Kehinde Idowu, and Saheed Sabiu. 2022. “Cheminformatics bioprospection of broad spectrum plant secondary metabolites targeting the spike proteins of omicron variant and wild-type SARS-CoV-2.” Metabolites 12(10): 982.
Barry, David. 2024. “The pros and cons of being an early adopter of digital transformation. Digital workplace.” https://www.reworked.co/digital-workplace/the-pros-and-cons-of-being-an-early-adopter-of-digital-transformation/. (Accessed 19 January 2024).
Bassey, Michael. 2001. “A solution to the problem of generalization in educational research: Fuzzy prediction.” Oxford Review of Education 27(1): 5‒22.
Bayram, Mustafa, Simon Springer, Colin K. Garvey, and Vural Özdemir. 2020. “COVID-19 digital health innovation policy: A portal to alternative futures in the making.” OMICS: A Journal of Integrative Biology 2020: 460‒469. http://doi.org/10.1089/omi.2020.0089.
Bhardwaj, Abhaya, Shristi Kishore, and Dhananjay K. Pandey. 2022. “Artificial intelligence in biological sciences.” Life 12(9): 1430.
Bitzer, E. M. 2008. “The professoriate in South Africa: Potentially risking status inflation.” South African Journal of Higher Education 22(2): 265‒281.
Black, Samantha. 2022. “What will digital transformation in research labs look like? The Science Advisory Board (Advancing the life sciences)”. https://www.scienceboard.net/index.aspx?sec=ser&sub=def&pag=dis&ItemID=3906. (Accessed 25 November 2023).
Bratko, Ivan and Stephen Muggleton. 1995. “Applications of inductive logic programming.” Communications of the ACM 38(11): 65‒70. https://doi.org/10.1145/219717.219771.
Breetzke, Gregory D. and David W. Hedding. 2018. “The changing demography of academic staff at higher education institutions (HEIs) in South Africa.” Higher Education 76: 145‒161.
Bresnahan, Timothy F. and Franco Malerba. 1999. “Industrial Dynamics and the Evolution of Firms’ and Nations’ Competitive Capabilities in the World Computer Industry.” In Sources of Industrial Leadership: Studies of Seven Industries, edited by David C. Mowery and Richard R. Nelson, 79‒132. Cambridge: Cambridge University Press.
Campbell, Ashley. 2022. “Life sciences digital transformation: The new era.” Last modified Sept 8, 2022. https://www.quanta-cs.com/blogs/2022-9/how-the-digital-transformation-is-impacting-the-life-science.
Chaudry, Rehan and Annelie Uvhagen. 2023. “The importance of digitalization for the future of life sciences.” https://www.technia.com/blog/the-importance-of-digitalization-for-the-future-of-life-sciences/. (Accessed 25 November 2023).
Cheema, Manraj Singh, Zulkefley Othman, Seri Narti Edayu Sarchio, Sharifah Sakinah Syed Alwi, Nur Fariesha Md Hashim, and Liew Chin Teng. 2022. “Teaching and learning of biosciences in a digital world: Challenges and effective teaching strategies during and after Covid-19 Pandemic.” Malaysian Journal of Medicine & Health Sciences 18: 144‒152.
Claptek. 2020. “How the digital transformation is impacting the life sciences industry.” https://claptek.com/blog/how-the-digital-transformation-is-impacting-the-life-sciences-industry/. (Accessed 22 November 2023).
Corporate Communication and Marketing Division Stellenbosch University. 2021. Taking potential professors into the future. Stellenbosch University, 26 July 2021. https://www.sun.ac.za/english/Lists/news/DispForm.aspx?ID=8427. (Accessed 24 February 2024).
Department of Higher Education and Training. 2020. “Minister Blade Nzimande: Coronavirus COVID-19 Alert Level 2 Measures in the Post School Education and Training Sector.” https://www.gov.za/speeches/minister-blade-nzimande-coronavirus-covid-19-alert-level-2-measures-post-school-education.
DHET see Department of Higher Education and Training.
Dohrmann, Michael. 2023. “Perspectives: Digital transformation in life sciences ‒ How pharma and medtech can shift from doing digital to being digital.” ttps://www2.deloitte.com/de/de/pages/life-sciences-and-healthcare/articles/gx-digital-transformation-in-life-sciences.html. (Accessed 23 November 2023).
Dolata, Ulrich and Raymund Werle. 2007. “Gesellschaft und die Macht der Technik: Sozioökonomischer und institutioneller Wandel durch Technisierung,” Schriften aus dem Max-Planck-Institut für Gesellschaftsforschung Köln No. 58, ISBN 978-3-593-38357-6. Campus Verlag, Frankfurt a. M.
Dolata, Ulrich. 2008. “The transformative capacity of new technologies. How innovations affect sectoral change: Conceptual considerations” MPIfG Discussion Paper, No. 08/2, Max Planck Institute for the Study of Societies, Cologne.
Dooley, Cian. 2021. “The digital transformation of L&D in life sciences.” https://www.intuition.com/the-digital-transformation-of-ld-in-life-sciences/. (Accessed 23 November 2023).
Dutta, Uma, Nikhil Danny Babu, and Girish S. Setlur. 2022. “Artificial intelligence in biological sciences: A brief overview.” Information Retrieval in Bioinformatics: A Practical Approach 2022: 19‒35.
eLabNext. 2023. “Digital transformation in life science and biotech R&D: A look into the SoCal bio scene.” Last modified March 16, 2023. https://www.elabnext.com/resource/blog/digital-transformation-in-biotech-rd-a-look-into-the-socal-bio-scene/.
George, Gerard, Ryan K. Merrill, and Simon J. D. Schillebeeckx. 2021. “Digital sustainability and entrepreneurship: How digital innovations are helping tackle climate change and sustainable development.” Entrepreneurship Theory and Practice 45: 999‒1027.
Gkrimpizi, Thomais, Vassilios Peristeras, and Ioannis Magnisalis. 2023. “Classification of barriers to digital transformation in higher education institutions: Systematic literature review” Education Sciences 13: 746. https://doi.org/10.3390/educsci13070746.
Hall, Peter A. and David Soskice. 2001. Varieties of capitalism: The institutional foundations of comparative advantage. Oxford: Oxford University Press.
Holzinger, Andreas, Karl Stampfer, Arne Nothdurft, Christoph Gollob, and Peter Kieseberg. 2022. “Challenges in artificial intelligence for smart forestry.” European Research Consortium for Informatics and Mathematics (ERCIM) News 130: 40‒41. https://ercim-news.ercim.eu/en130/r-i/challenges-in-artificial-intelligence-for-smart-forestry.
Holzinger, Andreas, Katharina Keiblinger, Petr Holub, Kurt Zatloukal, and Heimo Müller. 2023. “AI for life: Trends in artificial intelligence for biotechnology.” New Biotechnology 74(2023): 16‒24.
Holzinger, Andreas, Michael Kickmeier-Rust, and Heimo Müller. 2019. “Kandinsky patterns as IQ-test for machine learning.” In Machine Learning and Knowledge Extraction: Third IFIP TC 5, TC 12, WG 8.4, WG 8.9, WG 12.9 International Cross-Domain Conference, CD-MAKE 2019, Canterbury, UK, August 26–29, 2019, Proceedings 3: 1‒14. Springer International Publishing. https://doi.org/10.1007/978-3-030-29726-8-1.
Hyypiä, Mareena, Erkko Sointu, Laura Hirsto, and Teemu Valtonen. 2019. “Key components of learning environments in creating a positive flipped classroom course experience.” International Journal of Learning, Teaching and Educational Research 18(13): 61‒85.
Instituto de Tecnologia Química e Biológica 2023. “Digital transformations in biology.” https://www.itqb.unl.pt/digital-transformations-in-biology. (Accessed 23 November 2023).
Joshi, Naveen. 2021. “AI’s impact on biotechnology.” https://www.forbes.com/sites/naveenjoshi/2021/12/19/ais-impact-onbiotechnology/?sh=5dbb87852fb3. (Accessed 24 November 2023).
Kane, Gerald C., Doug Palmer, Anh Nguyen Phillips, David Kiron, and Natasha Buckley. 2015. “Strategy, not technology, drives digital transformation.” MIT Sloan Management Review 2015: 57181.
KMS Healthcare. 2023. “Guide to digital transformation in life sciences and biopharma.” Last modified January 12, 2023. https://kms-healthcare.com/guide-to-digital-transformation-in-life-sciences-biopharma/.
Lachman, Nirusha and Wojciech Pawlina. 2022. “Reconsidering laboratory‐based anatomy within the backdrop of digital transformation: Bringing an old practice into a new world.” Anatomical Sciences Education 15(3): 439‒446.
Langeloo, Annegien, Mayra Mascareño Lara, Marjolein I. Deunk, Nikolai F. Klitzing, and Jan-Willem Strijbos. 2019. “A systematic review of teacher–child interactions with multilingual young children.” Review of Educational Research 89(4): 536‒568. https://doi.org/10.3102/0034654319855619.
Malerba, Franco. 2004. Sectoral systems of innovation: Concepts, issues and analyses of six major sectors in Europe. Cambridge, MA: Cambridge University Press.
Marshall, Stephen J. 2018. Shaping the university of the future: Using technology to catalyse change. Springer, Singapore. 10: 978‒981. ISBN 9789811076190.
Mhlanga, David, Varaidzo Denhere, and Tankiso Moloi. 2022. “COVID-19 and the key digital transformation lessons for Higher Education Institutions in South Africa.” Education Sciences 12(7): 464. https://doi.org/10.3390/educsci12070464.
Mondejar, Maria E., Ram Avtar, Heyker Lellani Baños Diaz, Rama Kant Dubey, Jesús Esteban, Abigail Gómez-Morales, Brett Hallam et al. 2021. “Digitalization to achieve sustainable development goals: Steps towards a Smart Green Planet.” Science of The Total Environment 794: 148539.
Mospan, Natalia. 2023. “Trends in emergency higher education digital transformation during the COVID-19 pandemic.” Journal of University Teaching & Learning Practice 20(1): 50‒70. https://doi.org/10.53761/1.20.01.04.
Muggleton, Stephen H., Ute Schmid, Christina Zeller, Alireza Tamaddoni-Nezhad, and Tarek Besold. 2018. “Ultra-strong machine learning: Comprehensibility of programs learned with ILP.” Machine Learning 107: 1119‒1140. https://doi.org/10.1007/s10994-018-5707-3.
Müller, Heimo, Andreas Holzinger, Markus Plass, Luka Brcic, Cornelia Stumptner, and Kurt Zatloukal. 2022. “Explainability and causability for artificial intelligence-supported medical image analysis in the context of the European in vitro diagnostic regulation.” New Biotechnology 70: 67‒72. https://doi.org/10.1016/j.nbt.2022.05.002.
National Science Foundation US Report. 1995. “Bio-workshop report: Impact of emerging technologies on the biological sciences”. https://www.nsf.gov/bio/pubs/reports/stctechn/stcmain.htm. (Accessed 20 November 2023).
Nothdurft, Arne, Christoph Gollob, Ralf Kraßnitzer, Gernot Erber, Tim Ritter, Karl Stampfer, and Andrew O. Finley. 2021. “Estimating timber volume loss due to storm damage in Carinthia, Austria, using ALS/TLS and spatial regression models.” Forest Ecology and Management 502: 119714. https://doi.org/10.1016/j.foreco.2021.119714.
NSF US Report see National Science Foundation US Report.
Oloche, Jeremiah John, Bolaji Bosede Oluremi, Christiana Eleojo Aruwa, and Saheed Sabiu. 2023. “Molecular modeling identification of key secondary metabolites from Xylopia aethiopica as promising therapeutics targeting essential measles viral proteins.” Evidence-Based Complementary and Alternative Medicine 2023: 1575358. https://doi.org/10.1155/2023/1575358.
Organization for Economic Co-operation and Development. OECD. 2019. “Fostering science and innovation in the digital age.” OECD Going Digital Policy Note. OECD, Paris, www.oecd.org/goingdigital/fostering-science-and-innovation.pdf.
Paratela, Norton. 2023. “Biotechnology digital transformation.” LinkedIn Newsletter. https://www.linkedin.com/pulse/biotechnology-digital-transformation-norton-paratela/. (Accessed 22 November 2023).
Parker, Stephen. 2020. “The future of higher education in a disruptive world.” KPMG 2020, 1‒30. https://kpmg.com/xx/en/home/industries/government-public-sector/education/the-future-of-higher-education-in-a-disruptive-world.html.
Patrinos, George P. and Christina Mitropoulou. 2022. “Horizon scanning: Teaching genomics and personalized medicine in the digital age.” OMICS: A Journal of Integrative Biology 26(2): 101‒105. http://doi.org/10.1089/omi.2021.0119.
Penprase, B. Edward. 2018. “The fourth industrial revolution and higher education.” In Higher Education in the Era of the Fourth Industrial Revolution, edited by N. Gleason. Palgrave Macmillan, Singapore. https://doi.org/10.1007/978-981-13-0194-0_9.
Streeck, Wolfgang and Kathleen Thelen. 2005. “Introduction: Institutional change in advanced political economies.” In Beyond Continuity: Institutional Change in Advanced Political Economies, edited by Wolfgang Streeck and Kathleen Thelen, 1‒39. Oxford: Oxford University Press.
Sumatokhin, Sergey, Oksana Petrova, Delina Serovayskaya, and Fedor Chistiakov. 2020. “Digitalization of School Biological Education: Problems and Solutions.” In SHS Web of Conferences 79: 01016. EDP Sciences. https://doi.org/10.1051/shsconf/20207901016.
Thanachawengsakul, Nattaphol and Thanyavinichakul Akhaphan. 2020. “Education transformation into the role of higher education for local development.” Journal of Industrial Education 19(3): 131‒142.
Thompson, Desmond. 2023. “High praise for Future Professors initiative from its fellows.” University World News 17 August 2023. https://www.universityworldnews.com/post.php?story=20230801184729688. (Accessed 24 February 2024).
Trivedi, Pankaj, Jan E. Leach, Susannah G. Tringe, Tongmin Sa, and Brajesh K. Singh. 2020. “Plant–microbiome interactions: From community assembly to plant health.” Nature Reviews Microbiology 18(11): 607‒621. https://doi.org/10.1038/s41579-020-0412-1.
Tungpantong, Chanin, Prachyanun Nilsook, and Panita Wannapiroon. 2022. “Factors influencing digital transformation adoption among higher education institutions during digital disruption.” Higher Education Studies 12(2): 9‒19. https://doi.org org/10.5539/hes.v12n2p9.
Turing, Alan M. 1950. “Computing machinery and intelligence”. Mind LIX(236): 433–460. https://doi.org/10.1093/mind/LIX.236.433.
Verhoef, Peter C., Thijs Broekhuizen, Yakov Bart, Abhi Bhattacharya, John Qi Dong, Nicolai Fabian, and Michael Haenlein. 2021. “Digital transformation: A multidisciplinary reflection and research agenda.” Journal of Business Research 122: 889‒901.
Wong, Sybil, Mingke Pan, Allen Shaw, and Markus Gershater. 2022. “What digitalization in biology R&D means for biotech companies and life scientists.” Nature Biotechnology 40(7): 1151‒1153. https://doi.org/10.1038/s41587-022-01309-y.
Wouters, Olivier J., Martin McKee, and Jeroen Luyten. 2020. “Estimated research and development investment needed to bring a new medicine to market, 2009‒2018.” JAMA 323(9): 844‒853.
Xu, Jia, Pengwei Yang, Shang Xue, Bhuvan Sharma, Marta Sanchez-Martin, Fang Wang, Xu, Jia, Pengwei Yang et al. 2019. “Translating cancer genomics into precision medicine with artificial intelligence: Applications, challenges and future perspectives.” Human Genetics 138(2): 109‒124.
Young, Jeffery. 2017. “The new frontier in online education.” Slate 10 October 2017. http://www.slate.com/articles/technology/future_tense/2017/10/microcedentials_are_the_new_frontier_in_online_education.html.
Zhu, Yanjun, Zhiguo Cao, Hao Lu, Yanan Li, and Yang Xiao. 2016. “In-field automatic observation of wheat heading stage using computer vision.” Biosystems Engineering 143: 28‒41. https://doi.org/10.1016/j.biosystemseng.2015.12.015.
Zolkover, Andrii, Iaroslav Petrunenko, Olesia Iastremska, Oksana Stashkevych, and Mehriban Mehdiqizi Mehdizade. 2022. “Benefits and risks of digital business transformation: The example of eastern Europe countries.” Journal of Eastern European and Central Asian Research (JEECAR) 9: 344‒356.
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