Five-year outcomes of percutaneous coronary intervention using second generation drug-eluting stents for multivessel coronary artery revascularisation

  • A. Sahue Durban University of Technology
  • D.R. Prakaschandra Durban University of Technology
  • J.J. Patel University of KwaZulu-Natal
  • D.P. Naidoo University of KwaZulu-Natal https://orcid.org/0000-0002-7484-8456
DOI: https://doi.org/10.24170/22-1-5104

Abstract

Aim: This report evaluated outcomes of percutaneous coronary intervention (PCI) using drug-eluting stents (DESs) compared to coronary artery bypass grafts (CABG) for multivessel coronary artery disease (CAD).

Methods: Sixty patients (43M, 17F); mean = 64.35 years (SD ± 10.4) who underwent PCI or CABG were followed up for 5 years. Revascularisation included 19 elective and 5 emergency cases. The composite outcome (defined as major adverse cardiac and cerebral events [MACCE]), and rates of repeat revascularisation were compared in each group using survival curves and adjusted Cox pro-portional hazard models.

Results: Nine (15%) patients sustained acute MI  and 6 (10%) suffered a stroke during follow-up (PCI n=5, CABG  n=4). There were 10 deaths (DVD n=2, TVD n=8) (6 CABG, 4 PCI). There was no difference in treatment effects between the 2 groups for time to MI, stroke, and angina (PCI 40% vs. CABG 23.3%, p=0.194). Adjusted 5-year risk of death (11.7% vs. 17.6%, OR=1.300, CI=0.313 - 5.404, p=1.000) and the composite of death, stroke and MI (51.3% vs. 44% p=0.566) were similar in the 2 groups. There was a higher rate of repeat revascularisation in PCI group (52.8% vs. 29.3%) (p=0.121.)

Conclusions: PCI using DESs for patients with multivessel CAD showed similar outcomes to CABG.

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Author Biographies

A. Sahue, Durban University of Technology

Department of Biomedical and Clinical Technology, Durban University of Technology, Durban

D.R. Prakaschandra, Durban University of Technology

Department of Biomedical and Clinical Technology Durban University of Technology, Durban

J.J. Patel, University of KwaZulu-Natal

Department of Cardiology, University of KwaZulu-Natal, Durban

D.P. Naidoo, University of KwaZulu-Natal

Department of Cardiology, University of KwaZulu-Natal, Durban

Published
2025-03-07
Issue
Vol. 22 No. 1 (2025)
Section
Articles

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