Cyclophosphamide-induced melanonychia

Mazhar H Amirali, Mogamat-Yazied Chothia


A case of drug-induced melanonychia due to cyclophosphamide is described in a patient with lupus nephritis. This resolved completely at 20 weeks after stopping the drug. Clinicians should be aware of the causes of melanonychia, and, if drug-induced melanonychia is suspected, the offending drug should be stopped whenever possible.


cyclophosphamide; melanonychia; adverse drug reaction

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ISSN (online) 2518-4601 ISSN 2306-8205 (print). © African Association of Nephrology 2020.
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