Strategies in mechanical interventions for acute MI: facilitated and rescue PCI

Farrel Hellig


Primary Percutaneous Coronary Intervention (PCI) is the superior strategy for treating acute ST-elevation myocardial infarction (STEMI) as an initial strategy within the first 6 hours from symptom onset. Facilitation of PCI by the use of pre-treatment, prior to planned PCI, with thrombolytic drugs or glycoprotein (GP) IIb/IIIa inhibitors has held theoretical promise for earlier infarct related arterial patency, but has failed to deliver on such promise.
Thrombolysis as an initial strategy is inevitable in a large number of STEMI patients due to limited access to primary PCI. This strategy has limited success, and when it fails, rescue PCI has benefit and is recommended. Mechanical methods such as thrombectomy and distal protection, while having an intuitively plausible mechanism for benefit, have also failed to meet expectations and have a limited role in acute STEMI.

Full Text:




  • There are currently no refbacks.

ISSN: 2071-4602 (online) ISSN: 1996-6741 (print)

Copyright © 2017 SA Heart Journal

Hosted by Stellenbosch University Library and Information Service since 2017.

Creative Commons License -CC BY-NC-ND 4.0

This journal is hosted by the SU LIS on request of the journal owner/editor. The SU LIS takes no responsibility for the content published within this journal, and disclaim all liability arising out of the use of or inability to use the information contained herein. We assume no responsibility, and shall not be liable for any breaches of agreement with other publishers/hosts.