(Use MPC login credentials, the same you use to download your SA Heart congress CPD, or to participate in SA Heart nomination and voting. If you don’t have one yet, register a user login.)
Click on "Journal CPD" (Top row tab)
Find the SA Heart Journal, click on "Access"
Provide your SA Heart membership number (you can find this on your SA Heart member profile, using your email address to login on www.saheart.org ) or on your membership invoice.
Once you have provided your membership number, you will be able to access the journal and questionnaire and submit it once completed.
The long QT syndromes (LQTS) are Mendelian inherited conditions where syncope and sudden death are due to precipitous occurrence of polymorphic ventricular tachycardia. In South Africa a number of white, some coloured and some Asian individuals have been identified but, interestingly, not a single black person and neither has it been reported from Africa. With over 400 known causal-mutations, mostly in cardiac ion channel-genes, it is unlikely to be absent in African populations. LQTS is notorious for going undiagnosed or misdiagnosed, perhaps even more so in Africa. Amongst persons of Afrikaner descent the KCNQ1 A341V-mutation represents a founder effect. The availability of 170 living individuals sharing the same mutation has made it possible to study factors modifying risk. A blunted autonomic response has been shown to decrease risk of attacks.
Disclaimer: This journal is hosted by the SU LIS on request of the journal owner/editor. The SU LIS takes no responsibility for the content published within this journal, and disclaim all liability arising out of the use of or inability to use the information contained herein. We assume no responsibility, and shall not be liable for any breaches of agreement with other publishers/hosts.