Abstracts of the SA Heart Congress 2010
AbstractIntroduction: The pathophysiology of left ventricular (LV) remodelling in patients with hypertension (HT) is unclear.Aim: To evaluate the impact of four different types of geometric adaptations to hypertension on left ventricular ejection fraction (LVEF).Methods: A prospective single-centre study of 175 Black African patients (55% female, age = 53.1 ± 10.1 years) with moderate-to-severe HTwas performed. HT was defined as systolic or diastolic daytime ambulatory BP (ABPM) >140mmHg or 95mmHg respectively. Echocardiographywas performed using a HP 1 500 machine connected to 2.5 MHZ transducer. LV dimensions (LVEDD, LVESD, LVEF) were measuredusing standard American Society of Echocardiography definitions. Comparisons between the four geometric patterns were analysed using theKruskal-Wallis test.Conclusion: Patients with eccentric LVH have the lowest systolic performance as measured by LVEF. These results suggest that patients witheccentric LVH need more aggressive therapy for heart failure.
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