Abstracts of the SA Heart Congress 2010

  • Haroon Abbasi Division of Cardiology, Chris Hani Baragwanath Hospital, University of the Witwatersrand, Johannesburg
  • Elena Libhaber Division of Cardiology, Chris Hani Baragwanath Hospital, University of the Witwatersrand, Johannesburg
  • Gavin Norton Division of Cardiology, Chris Hani Baragwanath Hospital, University of the Witwatersrand, Johannesburg
  • Angela Woodiwiss Division of Cardiology, Chris Hani Baragwanath Hospital, University of the Witwatersrand, Johannesburg
  • Karen Sliwa Division of Cardiology, Chris Hani Baragwanath Hospital, University of the Witwatersrand, Johannesburg
  • Rafique Essop Division of Cardiology, Chris Hani Baragwanath Hospital, University of the Witwatersrand, Johannesburg

Abstract

Introduction: The pathophysiology of left ventricular (LV) remodelling in patients with hypertension (HT) is unclear.
Aim: To evaluate the impact of four different types of geometric adaptations to hypertension on left ventricular ejection fraction (LVEF).
Methods: A prospective single-centre study of 175 Black African patients (55% female, age = 53.1 ± 10.1 years) with moderate-to-severe HT
was performed. HT was defined as systolic or diastolic daytime ambulatory BP (ABPM) >140mmHg or 95mmHg respectively. Echocardiography
was performed using a HP 1 500 machine connected to 2.5 MHZ transducer. LV dimensions (LVEDD, LVESD, LVEF) were measured
using standard American Society of Echocardiography definitions. Comparisons between the four geometric patterns were analysed using the
Kruskal-Wallis test.
Conclusion: Patients with eccentric LVH have the lowest systolic performance as measured by LVEF. These results suggest that patients with
eccentric LVH need more aggressive therapy for heart failure.
Published
2017-04-10
Section
Congress Proceedings