Mind the gap in kidney care: translating what we know into what we do

  • Valerie A Luyckx University of Zurich
  • Katherine R Tuttle University of Washington
  • Dina Abdellatif Cairo University Hospital
  • Ricardo Correa-Rotter Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
  • Winston WS Fung Chinese University of Hong Kong
  • Agnès Haris Péterfy Hospital
  • Li-Li Hsiao Harvard Medical School
  • Makram Khalife ISN Patient Liaison Advisory Group
  • Latha A Kumaraswami Tamilnad Kidney Research (TANKER) Foundation
  • Fiona Loud ISN Patient Liaison Advisory Group
  • Vasundhara Raghavan ISN Patient Liaison Advisory Group
  • Stefanos Roumeliotis AHEPA University Hospital Medical School
  • Marianella Sierra ISN Patient Liaison Advisory Group
  • Ifeoma Ulasi University of Nigeria
  • Bill Wang ISN Patient Liaison Advisory Group
  • Siu-Fai Lui The Chinese University of Hong Kong Jockey Club School of Public Health and Primary Care
  • Vassilios Liakopoulos AHEPA University Hospital Medical School
  • Alessandro Balducci Italian Kidney Foundation Italy


Historically, it takes an average of 17 years to move new treatments from clinical evidence to daily practice. Given the highly effective treatments now available to prevent or delay kidney disease onset and progression, this is far too long. The time is now to narrow the gap between what we know and what we do. Clear guidelines exist for the prevention and management of common risk factors for kidney disease, such as hypertension and diabetes, but only a fraction of people with these conditions worldwide are diagnosed, and even fewer are treated to target. Similarly, the vast majority of people living with kidney disease are unaware of their condition, because in the early stages it is often silent. Even among patients who have been diagnosed, many do not receive appropriate treatment for kidney disease. Considering the serious consequences of kidney disease progression–kidney failure or death–it is imperative that treatments are initiated early and appropriately. Opportunities to diagnose and treat kidney disease early must be maximized beginning at the primary care level. Many systematic barriers exist, ranging from patient to clinician to health systems to societal factors. To preserve and improve kidney health for everyone everywhere, each of these barriers must be acknowledged so that sustainable solutions are developed and implemented without further delay.


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How to Cite
Luyckx, Valerie A, Katherine R Tuttle, Dina Abdellatif, Ricardo Correa-Rotter, Winston WS Fung, Agnès Haris, Li-Li Hsiao, Makram Khalife, Latha A Kumaraswami, Fiona Loud, Vasundhara Raghavan, Stefanos Roumeliotis, Marianella Sierra, Ifeoma Ulasi, Bill Wang, Siu-Fai Lui, Vassilios Liakopoulos, and Alessandro Balducci. 2024. “Mind the Gap in Kidney Care: Translating What We Know into What We Do”. African Journal of Nephrology 27 (1), 34-45. https://doi.org/10.21804/27-1-6455.