Cardiovascular disease in chronic kidney disease – a review of risk factors

  • Muzamil Olamide Hassan Obafemi Awolowo University, Ile-Ife, Nigeria
  • Stephen Olawale Oguntola St. Nicholas Hospital https://orcid.org/0000-0001-5442-6195
  • Raquel Duarte
  • Saraladevi Naicker Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, South Africa

Abstract

Patients with chronic kidney disease (CKD) are at increased risk of cardiovascular disease (CVD), such that the risk of cardiovascular mortality is greater than the risk of progression to end-stage kidney disease. Despite the increased prevalence of traditional and non-traditional cardiovascular risk factors, patients with kidney disease have been mostly under-represented in previous cardiovascular outcome studies, thereby resulting in a paucity of data on the evidence-based management of CVD in CKD. In this review, we explore the evidence on the burden of CVD and its risk factors in patients with CKD, highlight various inflammatory biomarkers for predicting CVD and provide an overview on novel biomarkers for CVD.

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Author Biographies

Muzamil Olamide Hassan, Obafemi Awolowo University, Ile-Ife, Nigeria
Department of Medicine, Obafemi Awolowo University, Ile-Ife, Nigeria / Lecturer 1
Stephen Olawale Oguntola, St. Nicholas Hospital

St. Nicholas Hospital, Department of Medicine (Nephrology and Kidney Transplant Unit) / Consultant Nephrology

Raquel Duarte
Internal Medicine Research Laboratory, Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, South Africa / Professor of Molecular Biology and Head of Internal Medicine Laboratory
Saraladevi Naicker, Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, South Africa
Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, South Africa / Emeritus Professor of Medicine
Published
2020-08-11
How to Cite
Hassan, Muzamil Olamide, Stephen Olawale Oguntola, Raquel Duarte, and Saraladevi Naicker. 2020. “Cardiovascular Disease in Chronic Kidney Disease – a Review of Risk Factors”. African Journal of Nephrology 23 (1), 152-58. https://doi.org/10.21804/23-1-3960.
Section
Reviews